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Third-party lab tested in the USA

Certificate of Analysis

Independent analysis of this lot by Kovera Labs (HPLC-UV).

Purity
99.7%
Lot
ML-260908
Tested Most recent
Sep 2026

DSIP Peptide

In Stock
CAS
62568-57-4
Molecular weight
848.81 g/mol
Form
Lyophilized powder
Purity (HPLC)
99.7% HPLC-UV
Storage
-20°C or colder
Lot / COA
Quantity
Size
5mg
Quantity
DSIP5 mg · Qty 1Order Now, Ships Within 24 Hours
$50
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Research Use Only

For laboratory research use only. Not for human consumption. All products are intended solely for laboratory research and are not for human or animal consumption. By purchasing, the buyer agrees to use these products in compliance with all applicable laws.

Specifications

CAS
62568-57-4
Molecular formula
C35H48N10O15
Molecular weight
848.81 g/mol
Form
Lyophilized powder
Purity (HPLC)
99.7% HPLC-UV
Storage
-20°C or colder
Lot / COA
PubChem CID
68816
Third-party lab tested in the USA

Certificate of Analysis

Independent analysis of this lot by Kovera Labs (HPLC-UV).

Purity
99.7%
Lot
ML-260908
Tested Most recent
Sep 2026

DSIP Peptide Overview

DSIP peptide, named for the descriptor delta sleep-inducing peptide, is a small amphiphilic peptide consisting of nine amino acids (Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu) with demonstrated effects on circadian signaling and neuroendocrine regulation in experimental models. Originally identified through its ability to modulate delta-wave patterns in experimental systems, DSIP has been studied for its influence on circadian rhythms, electroencephalographic patterns, and hypothalamic-pituitary-adrenal (HPA) axis activity. Research indicates potential modulatory effects on GABAergic and serotonergic signaling systems, corticosterone and ACTH dynamics, and oxidative stress responses in laboratory settings.

Schoenenberger & Monnier (1977).

Related neuropeptide research materials in the Medicina Labs catalog include Semax and Selank.

For discovery history and the state of the evidence, see What Is DSIP?

History

DSIP was first isolated in 1977 by Monnier, Schoenenberger, and colleagues from the cerebral venous blood of rabbits during slow-wave induction experiments. Initial studies demonstrated that intraventricular administration of this peptide promoted delta-frequency EEG patterns consistent with slow-wave activity. Since its discovery, DSIP has been investigated across neuroscience, endocrinology, and circadian research disciplines for its diverse neuromodulatory properties.

Monnier et al. (1977).

DSIP Structure

CAS #: 62568-57-4
Molecular Formula: C35H48N10O15
Molecular Weight: 848.81 g/mol
PubChem ID: 68816

Research Findings

DSIP has been examined in circadian and neuroendocrine research, with investigations focusing on EEG pattern modulation, HPA axis dynamics, neurotransmitter system interactions, and neuronal signaling effects in various experimental models. Studies explore its influence on circadian biology and molecular stress responses.

Key Areas of Research:

  • Circadian: Delta-wave, REM modulation, entrainment
  • Neuroendocrine: Corticosterone, ACTH, HPA axis
  • Signaling: GABAergic, serotonergic, dopaminergic
  • Neuronal: Oxidative stress, calcium dynamics, viability

Together, these findings demonstrate DSIP's multifaceted actions across circadian, endocrine, and neuronal signaling systems. As a naturally occurring neuropeptide, DSIP provides a research framework for examining circadian dynamics, stress adaptation mechanisms, and neuroendocrine integration in diverse experimental paradigms.

Schoenenberger & Monnier, Proceedings of the National Academy of Sciences, 1977

Our Process

Lab technician examining a sample under a microscope
Step 1

Precision Lyophilization

Each batch is freeze-dried and sealed for stability until reconstitution.

Lab technician inspecting vials for purity testing
Step 2

Verified Purity

Every batch is third-party tested with HPLC and mass spectrometry.

Packaged order ready for shipment
Step 3

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Orders ship within 24 hours from our U.S. facility.

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Purity is measured by HPLC (High-Performance Liquid Chromatography), which separates and quantifies each component in a sample. The result is reported as a percentage on the Certificate of Analysis (COA), along with the chromatogram, for every batch.
All our peptides are tested by independent third-party labs and consistently achieve 99%+ purity. Every product ships with a Certificate of Analysis so you can verify the exact purity of your specific batch.
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DSIP 5mg · Qty 1
5mg $50