LP1-S Peptide
Out of stock$130/ vial
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Specifications
Specifications
- CAS
- 910463-68-2
- Molecular formula
- C187H291N45O59
- Molecular weight
- ~4114 g/mol
- Form
- Lyophilized powder
- Purity (HPLC)
- COA pending
- Storage
- -20°C or colder
- Lot / COA
- Pending
- PubChem CID
- 56843331
About
LP1-S Peptide Overview
LP1-S is a synthetic peptide analog designed for selective activity at the glucagon-like peptide-1 receptor (GLP-1R). Structural modifications to the native GLP-1 framework increase resistance to enzymatic degradation and extend receptor activity, making the compound useful in experimental models examining endocrine signaling and metabolic pathway regulation. LP1-S is the Medicina Labs catalog designation for this material; its identity is defined by the CAS registry number, molecular formula, and PubChem identifier listed in the structure section below.
Research involving LP1-S has examined receptor activation, intracellular signaling cascades, glucose-associated regulatory pathways, lipid signaling, and central endocrine mechanisms.
Related receptor-signaling research materials in the Medicina Labs catalog include LP3-R and Cagrilintide.
History
LP1-S emerged from decades of research into GLP-1 biology and the development of more stable analogs of endogenous GLP-1. Native GLP-1 is rapidly degraded, creating interest in modified peptides capable of maintaining receptor activity for substantially longer periods.
Medicinal chemistry research ultimately produced a modified GLP-1 analog incorporating amino-acid substitutions and fatty-acid conjugation to increase molecular stability and albumin association. The compound's development was described in detail by Lau and colleagues in 2015.
LP1-S Structure
CAS #: 910463-68-2
Molecular Formula: C187H291N45O59
Molecular Weight: ~4114 g/mol
PubChem ID: 56843331
Research Findings
LP1-S has been examined across receptor, endocrine, cellular, and systemic experimental models. Research has focused on GLP-1 receptor activity and the intracellular pathways activated following receptor engagement.
Key Areas of Research:
- Receptor: GLP-1R binding and activation
- Endocrine: Glucose-associated signaling pathways
- Molecular: cAMP-mediated signaling and downstream cascades
- Systemic: Metabolic, lipid, and energy-regulation pathways
Together, these findings provide a framework for investigating selective GLP-1 receptor biology and the downstream molecular processes that follow sustained receptor activation.
Specifications, Testing & Storage
LP1-S is supplied in 5mg, 10mg, 15mg, and 30mg sizes as lyophilized (freeze-dried) powder in sealed glass vials, each labeled with the product name, lot number, quantity, and storage instructions.
Purity is measured by HPLC (High-Performance Liquid Chromatography), and a Certificate of Analysis is available for every batch. Lyophilized material should be stored at -20°C or colder upon arrival.
LP1-S is supplied strictly for laboratory research use only and is not intended for human or animal use.
Storage & handling
Store sealed vials at -20°C or colder, protected from light. Supplied as a lyophilized powder in a sealed glass vial.
Shipping
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