Certificate of Analysis
Independent analysis of this lot by Kovera Labs: HPLC purity and mass-spec identity.
- Purity
- 99.43%
- Lot
- ML-260929
- Tested Most recent
- Sep 2026
LP2-T Peptide
In stock99.43% purity (HPLC)
$140/ vial
$140$112 first-order price save $28 total20% off (SHOP20), auto-applied in cart
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Certificate of Analysis
Independent analysis of this lot by Kovera Labs: HPLC purity and mass-spec identity.
- Purity
- 99.43%
- Lot
- ML-260929
- Tested Most recent
- Sep 2026
Specifications
Specifications
- CAS
- 2023788-19-2
- Molecular formula
- C225H348N48O68
- Molecular weight
- ~4813 g/mol
- Form
- Lyophilized powder
- Purity (HPLC)
- 99.43% HPLC-UV
- Storage
- -20°C or colder
- Lot / COA
- PubChem CID
- 156588324
About
LP2-T Peptide Overview
LP2-T is a synthetic peptide engineered as a dual agonist of the glucose-dependent insulinotropic polypeptide receptor (GIPR) and glucagon-like peptide-1 receptor (GLP-1R). Its dual-receptor profile allows researchers to examine interactions between two related incretin signaling systems within a single experimental model. LP2-T is the Medicina Labs catalog designation for this material; its identity is defined by the CAS registry number, molecular formula, and PubChem identifier listed in the structure section below.
Studies involving LP2-T have focused on receptor pharmacology, intracellular signaling, endocrine regulation, metabolic pathway dynamics, and potential synergistic effects produced by simultaneous GIPR and GLP-1R activation.
History
The development of LP2-T followed advances in selective GLP-1 receptor agonist research. Investigators hypothesized that simultaneously engaging GIP and GLP-1 signaling could produce a distinct integrated biological response compared with targeting either pathway independently.
Researchers at Eli Lilly developed a 39-amino-acid synthetic peptide based in part on the GIP sequence and engineered it to activate both GIP and GLP-1 receptors while incorporating structural modifications that extend molecular activity. The compound was described in detail by Coskun and colleagues in 2018.
LP2-T Structure
CAS #: 2023788-19-2
Molecular Formula: C225H348N48O68
Molecular Weight: ~4813 g/mol
PubChem ID: 156588324
Research Findings
LP2-T has been investigated across endocrine, receptor, metabolic, and intracellular signaling models. Of particular research interest is the interaction between GIPR and GLP-1R signaling and the potential for coordinated activity across the two receptor systems.
Key Areas of Research:
- Dual Receptor: GIPR and GLP-1R activation
- Endocrine: Integrated incretin signaling
- Molecular: Receptor crosstalk and downstream cascades
- Systemic: Glucose, lipid, and energy-regulation pathways
Together, these findings make LP2-T a research platform for examining dual-receptor pharmacology and the biological consequences of coordinated GIP and GLP-1 pathway activation.
Specifications, Testing & Storage
LP2-T is supplied in 10mg and 30mg sizes as lyophilized (freeze-dried) powder in sealed glass vials, each labeled with the product name, lot number, quantity, and storage instructions.
Purity is measured by HPLC (High-Performance Liquid Chromatography), and a Certificate of Analysis is available for every batch. Lyophilized material should be stored at -20°C or colder upon arrival.
LP2-T is supplied strictly for laboratory research use only and is not intended for human or animal use.
Storage & handling
Store sealed vials at -20°C or colder, protected from light. Supplied as a lyophilized powder in a sealed glass vial.
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