Certificate of Analysis
Independent analysis of this lot by Kovera Labs (HPLC-UV).
- Purity
- 99.82%
- Lot
- ML-260928
- Tested Most recent
- Sep 2026
Thymosin Alpha-1 Peptide
In Stock- CAS
- 62304-98-7
- Molecular weight
- 3108.28 g/mol
- Form
- Lyophilized powder
- Purity (HPLC)
- 99.82% HPLC-UV
- Storage
- -20°C or colder
- Lot / COA
- Free shippingOn every order
- Free 2nd Day AirOn orders $200+
Research Use Only
For laboratory research use only. Not for human consumption. All products are intended solely for laboratory research and are not for human or animal consumption. By purchasing, the buyer agrees to use these products in compliance with all applicable laws.
Specifications
- CAS
- 62304-98-7
- Molecular formula
- C129H215N33O55
- Molecular weight
- 3108.28 g/mol
- Form
- Lyophilized powder
- Purity (HPLC)
- 99.82% HPLC-UV
- Storage
- -20°C or colder
- Lot / COA
- PubChem CID
- 16130571
Certificate of Analysis
Independent analysis of this lot by Kovera Labs (HPLC-UV).
- Purity
- 99.82%
- Lot
- ML-260928
- Tested Most recent
- Sep 2026
Thymosin Alpha-1 Peptide Overview
The Thymosin Alpha-1 peptide — also written Thymosin Alpha 1, and abbreviated Tα1 or TA-1 — functions as a potent immunomodulator that influences signaling dynamics, cytokine expression, and immune pathway homeostasis. As a naturally occurring 28-amino acid peptide originally isolated from thymic tissue, Tα1 has been studied for its role in thymocyte signaling, immune pathway differentiation, and innate and adaptive response regulation. Through toll-like receptor (TLR) pathway activation and signaling modulation, Tα1 has been investigated in research models examining thymocyte dynamics, dendritic signaling, natural killer pathway activity, and multi-system immune responses in laboratory settings.
Wei et al. (2023). Romani et al. (2007).
Thymalin is a related thymus-derived research material in the Medicina Labs catalog; unlike Thymosin Alpha-1 it is a polypeptide mixture rather than a single defined sequence.
History
Thymosin Alpha 1 was first isolated and characterized from bovine thymus gland in the 1970s by Allan Goldstein and colleagues at George Washington University. This peptide was identified as the primary active component of thymosin fraction 5, a crude thymic extract with immunological activity. Subsequent research established its role in thymocyte differentiation and led to development as thymalfasin for continued experimental investigation.
Thymosin Alpha-1 Structure
CAS #: 62304-98-7
Molecular Formula: C129H215N33O55
Molecular Weight: 3108.28 g/mol
PubChem ID: 16130571
Research Findings
Thymosin Alpha 1 has been examined in immunology research focusing on thymocyte signaling, cytokine modulation, toll-like receptor signaling, and age-associated immune pathway changes in various experimental models. Studies investigate its effects on lymphocyte populations, dendritic signaling, and immune pathway dynamics across different experimental contexts.
Key Areas of Research:
- Thymocyte: Maturation, CD4/CD8, thymic dynamics
- Immunomodulation: Cytokine, dendritic, IFN-γ
- Pathway: TLR, receptor expression, antigen
- Systemic: NK activity, age-associated, signaling
Together, these investigations reveal Tα1's broad immunomodulatory properties across immune signaling pathways and experimental systems. Through TLR-dependent and independent mechanisms, Tα1 serves as a research tool for examining immune pathway dynamics, differentiation cascades, and age-associated signaling changes in preclinical models and assay-based systems.
Our Process
Precision Lyophilization
Each batch is freeze-dried and sealed for stability until reconstitution.
Verified Purity
Every batch is third-party tested with HPLC and mass spectrometry.
Careful Fulfillment
Orders ship within 24 hours from our U.S. facility.